Our Lab

Figure 1. Circos plots of somatic point mutations and copy number mutations identified in cutaneous T cell. lymphoma. Point mutations are indicated by black triangles; deletions, light blue boxes; amplifications, red boxes; translocations, royal blue lines; intrachromosomal rearrangements, green lines.

Our Scientific Approach
We employ cutting-edge genomics approaches to identify the genetic basis of skin cancers and inherited and acquired immunological disorders. Learn more about recent publications from the lab.

Current Projects:

  1. Gene Discovery: We are using cutting edge next generation sequencing to identify the genetic basis of other inherited and acquired skin diseases and cancers.
  2. Molecular Mechanisms: We are using human and animal models to determine how mutations we have discovered affect disease pathogenesis.
  3. Clinical Translation: We are actively studying methods to translate our findings into clinically useful biomarkers and novel therapeutics.

We are looking for motivated, energetic postdoctoral fellows, graduate students, and bioinformaticians to join the Choi lab. If you are interested, please contact us:

Jaehyuk Choi
Northwestern University Feinberg School of Medicine
303 East Superior St.
Chicago, IL 60611

“Cancer was not disorganized chromosomal chaos. It was organized chromosomal chaos.”
Siddhartha Mukherjee, The Emperor of All Maladies: A Biography of Cancer